ANTRLRequest a briefing

Evidence tiers

A controlled vocabulary for every claim, so readers can tell an established finding from a working model or an idea.

Reviewed 3 November 2026

The four tiers

ATS-1 evidence tiers
TierDefinitionInformative grade
EstablishedFindings repeated across studies in the cited literatureHigh to moderate certainty
ModelAn accepted framework, applied by ATS-1 as a modelModerate to low certainty
HypothesisTestable, not yet tested for this useLow to very low certainty
InspirationGuides thinking; never offered as evidence; no output depends on itNot graded

The current claims register

ATS-1 claims register (current)
ClaimTier
Energy is never created or destroyed; food energy goes to work, storage or heatEstablished
Light is the main signal keeping the 24-hour clock in stepEstablished
The clock influences moodModel
Allostasis: the body anticipates demand and pays a costModel
Early-warning signals before changes in depression (group level)Model
Cross-plane early-warning signalsHypothesis
Exercise reduces depressive symptoms (low-to-moderate certainty)Established
Mitochondria and psychological stress interact (mostly animal evidence)Model
Free-energy principle (a framework, not one quantity)Model
Mind as a quantum processInspiration (not used in any measure)

Sources for each claim are listed in the specification.

How a claim moves

A claim moves up a tier only when the evidence changes, and every change is versioned. ANTRL's first preregistered claim is that cross-plane early-warning signals predict a self-reported wellbeing shift better than either plane alone; it carries the Hypothesis tier until tested. See governance.

Questions

Why include Inspiration at all?

Because ideas shape research. Labeling them Inspiration makes clear they are not evidence and that no output depends on them.

Keep reading

Take the next step.

The ATS-1 evidence tiers (Established, Model, Hypothesis, Inspiration), their definitions, and the current register of claims.